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Fig. 1. Ptpmeg homologs, locus structure and mutations. (A)
Drosophila and human Ptpmeg family proteins. The
ptpmeg1 mutation is indicated. (B) ptpmeg
locus with the major transcripts, ptpmeg2 insertion and
ptpmeg1 mutation indicated. (C) Sequence trace
showing ptpmeg1 mutation. (D)
ptpmeg1 produces no detectable full-length Ptpmeg, whereas
ptpmeg2 reduces Ptpmeg expression. Asterisk indicates
background band. Elav is loading control.