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Figure 7


Fig. 7. ptpmeg is required for normal ellipsoid body development. (A) Ellipsoid body (EB; darker part of diagram). EB axon termini form a ring labeled with anti-Fasciclin II in B-G. (B) 48h PPF control EB axon ring. (C) 48 hours PPF ptpmeg mutant EB rings are often open ventrally (arrowhead). (D) EB axons in control adult. (E,F) In ptpmeg mutant adults, EB ring is often open (arrowheads). (G) Ptpmeg expression in neurons rescues ptpmeg EB defects. (H,I) EB neurons visualized using EB1-Gal4;UAS-mCD8:GFP. (H) Control. EB cell bodies (bracket) extend a fascicle that branches to a dendritic region (asterisk) and to axons that form the ring. (I) ptpmeg mutant. EB axons are slightly defasciculated (arrow) and do not elaborate a normal ring (arrowhead). (J) ptpmeg is not required in the EB cells. Homozygous ptpmeg1 mutant EB neuron (marked in green) in otherwise heterozygous animal.





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