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Fig. 3. Nanos2 can rescue the postnatel defects in Nanos3-/- testes
and ovaries. Testis samples were prepared from littermates of
Nanos3+/+, Nanos3+/- or Nanos3-/-, or from
littermates of Nanos3-/- expressing the FLAG-tagged Nanos2
transgene, at 2 weeks (A-D) and 6 weeks (E-H) after birth. The
testis weights of different genotypes were compared at 6 weeks (I). The
testis weight of Nanos3+/- was designated as 100%. Ovary samples
were prepared from Nanos3+/- (J), Nanos3-/-
(K) and Nanos3-/- harboring the Nanos2 transgene (L)
at 6-7 weeks after birth. The genotypes are indicated in each panel. Germ
cells were detected by immunostaining with TRA104 (B-D) and TRA98 (F-H)
antibodies. Scale bars: 100 µm in C for B-D; 100 µm in G for F-H; and
100 µm in K for J-L.
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