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Fig. 6. Ectopic expression of either Wnt5 or Wnt4 is
sufficient to repel the salivary glands. (A-C) Lateral views of
stage 16 Drosophila embryos stained for FKH and CRB. (B) WNT5 was
ectopically expressed in the visceral mesoderm, dorsal to the gland (located
above the gland in these panels). The misexpression of WNT5 is sufficient to
redirect the tip of the salivary gland ventrally. (C) When Wnt4 is
ectopically expressed in the visceral mesoderm, it is sufficient to repel the
entire salivary gland away from the visceral mesoderm. These data support the
hypothesis that both Wnt proteins act as repellents.