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Figure 5


Fig. 5. Inactivating M/Z Ena does not disrupt cell adhesion. F-actin (except I,J, DE-cad). (A-J) Extended germband. mat-FP4mito and M/Zena23. Morphology (A-D), cortical actin (E-H) and DE-cad (I,J) normal. (K,L) Early germband retraction. mat-FP4mito (L) amnioserosal cells (brackets) do not overlap posterior epidermis (arrows) to the same extent as wild type (K). Smaller cell size in mat-FP4mito is probably because of overall smaller size of embryos, because of defects in nurse cell dumping. (M-P) Germband retraction. (M,N) Wild-type. Amnioserosa and epidermis maintain close contact throughout (arrows). (O,P) mat-FP4mito. Arrows, amnioserosa detached from epidermis. Arrowheads in P, deep segmental grooves. Scale bars: 20 µm.





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