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Figure 1


Fig. 1. Opposing effects of nmo and the Dpp pathway on Drosophila wing growth and patterning. (A) A wild-type adult wing. (B,C) Wings from transheterozygous combinations of dpp loss-of-function alleles (B, dppd5/dpphr56; C, dppd5/dpphr4) show reductions in vein spacing and loss of veins. (D-F) Ectopic Nemo decreases spacing of veins in a dose-sensitive manner. (D) omb-Gal4/+; UAS-nemo/+. (E,F) omb-Gal4/+; UAS-nmo/+; UAS-nmo/+. (G) UAS-Mad/+; vg-Gal4/+. (H) A nmoadk2/nmoadk2 loss-of-function wing. (I) Ectopic expression of the BMP antagonist Sog (UAS-sog/+; 69B-Gal4/+). (J) UAS-nmo/+; 69B-Gal4/+ phenocopies reduced BMP signaling.





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