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Figure 6


Fig. 6. Mutations in the Drosophila lkb1 gene disrupt Baz/Par-6/DaPKC but not Pins/G{alpha}i localization at the NB apical pole. (A) Pins, G{alpha}i, Baz, Par-6 and DaPKC localization in wild-type and dlkb1315/dlkb1315 mutants. NBs in the first row were simultaneously stained for Pins, Centrosomin (Cnn) and DNA (blue). Cells shown in the subsequent rows were stained for tubulin (Tub), DNA (blue) and either G{alpha}i, Baz, Par-6 or DaPKC. Scale bar: 5 µm. (B) Frequencies of NBs with Pins, G{alpha}i, Baz, Par-6 and DaPKC crescents in wild-type and dlkb1315/dlkb1315 mutant brains.





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