DEV004929 Supplementary Material

Files in this Data Supplement:

• Supplemental Figure S1 -

  Fig. S1. Loss of Fgf8b alters the expression domains of Nodal, Cer1 and Fgf8 relative to the shape of the embryo. Expression of Nodal (A,B), Cer1 (C,D) and Fgf8 (E,F) in wild-type (WT) and Fgf8^Δb/Δb embryos at E6.5. Images to the left show the lateral view (anterior to the right); images to the right show the distal view (C,D) or posterior view (A,B and E,F) of the same embryo. Asterisk marks the posterior pole of the epiblast.

• Supplemental Figure S2 -

  Fig. S2. Dynamic changes in Fgf8 expression in pregastrular embryos. Expression of Fgf8 in embryos at E5.75 (A) and E6.25 (B). Arrowhead and arrow mark the AVE and posterior epiblast, respectively.