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Fig. 5. Regulation of Dpp inhibitors by Grk and Dpp signaling. Anterior is to the left. Lateral view of stage 10B egg chambers. Only the posterior half of the egg chambers is shown. (A,C,E,G,I,K,M) RNA in situ hybridization for dSno. (B,D,F,H,J,L,N) RNA in situ hybridization for brk. The same genotypes are used as in Fig. 3. (A,B) Wild type. (C,D) Moderate misexpression of dpp. (E,F) Strong misexpression of dpp. (G,H) Strong misexpression of grk. Inset in H shows the shift of brk expression to the ventral follicle cells in moderate misexpression of grk. (I,J) Strong misexpression of grk and moderate misexpression of dpp. (K,L) Strong misexpression of grk and dpp. (M,N) grk^HF/grk^2B6. (O,P) Double immunofluorescence for ß-gal (red) and GFP (green). dSno expression (dSno-lacZ) is downregulated cell autonomously in Med¹³ mutant follicle cell clones. White lines mark the clone boundaries.

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