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Figure 4


Fig. 4. Time-lapse analysis of migratory behaviour of Cdk5-/- neurons. (A) Cdk5+/+ and Cdk5-/- mouse embryos were infected with Adex-CAG-Lyn-Venus at E12.5, and brain slice cultures were started at E14.5. Representative images are shown of migrating neurons after 24 hours (24 h) and 48 hours (48 h) of culture. Scale bar 10 µm. (B) GFP-positive neurons were classified as multipolar or bipolar by their morphology and behaviour at 24 and 48 hours, and the percentage is shown for each genotype. *, P<0.01.





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