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Fig. 7. Comparison between the mouse and zebrafish Hox gene clusters. Only
the numbers of genes and their paralogy groups are shown for comparison, along
with the sizes (scale bar on top) of the various clusters. The four murine (M)
clusters are shown with Hox genes in black and, below, their zebrafish (ZF)
Hox gene counterparts in gray. Mouse Hoxa, Hoxb and Hoxc
clusters have two zebrafish counterparts, whereas the mouse Hoxd
cluster has a single orthologous cluster in zebrafish. On the right, both the
number of genes per cluster and the sizes (kb) of the respective clusters are
shown. Totals are given at the bottom, which show that despite zebrafish
having the higher number of clusters and a slight increase in Hox gene number,
the overall lengths obtained when all clusters are artificially considered
together are virtually identical in the two animals. *, The
position of the mouse Hoxb13 gene is not shown at the correct scale,
as it is located
100 kb from Hoxb9 (see text). The Hoxb
cluster is
200 kb, which makes the overall length of the four murine
clusters even larger than that of the seven fish counterparts.
, A ZFHoxDb `cluster' is shown, even in the absence of Hox
genes, as this cluster was selectively lost, as indicated by the structure of
the remaining genomic locus (Woltering and
Durston, 2006).