|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 1. Ahd2 expression marks a specific mdDA subpopulation in the adult
brain. (A) Coronal sections from the rostral (R) to caudal (C) mdDA
area containing neurons in the SNc (A-D) and VTA
(E-L). (Left panels) The cell bodies of these mdDA
neurons were identified by Th mRNA expression. (Right panels)
Analysis of Ahd2 expression on adjacent sections. (B) Combined
in situ hybridization for Ahd2 mRNA (purple) and an
immunohistochemical staining for TH protein (brown) on adult coronal sections.
The boxed areas indicated in A and D are displayed at a
higher magnification in the panels B and C, and
E and F, respectively. (C) Adult coronal sections
of the SNc (A-C,G-I) and VTA
(D-F,J-L).
(B,E) Ahd2 protein distribution (red). MdDA neurons were
identified by the expression of TH protein (green; A,D).
Overlays demonstrate the co-expression of the TH and Ahd2 proteins in a
subpopulation of mdDA neurons located in the SNc and VTA
(C,F-L). The boxed areas indicated in
G and J are displayed at a higher magnification in
H and I, and K and L,
respectively. mdDA, meso-diencephalic dopaminergic; SNc. substantia nigra pars
compacta; VTA, ventral tegmental area.
|
