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Figure 5


Fig. 5. TAF4 has tumour suppressor activity. (A) Quantitation of tumours in oil- and Tam-injected mice after DMBA/TPA treatment. N, number of animals per group. (B) Number and size of tumours from oil- or Tam-injected animals after 26 weeks of treatment. (C) Quantitation of tumours in animals treated with DMBA and TPA for 15 weeks prior to oil or Tam injection. (D) Quantitation of tumours in oil- and Tam-injected animals after two sequential DMBA treatments. (E) Representative animals after 20 weeks of DMBA/TPA treatment. Black arrows, epidermal tumours; yellow arrows, melanocytic growths. (F) Representative animals after 20 weeks of DMBA treatment.





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