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Fig. 2. Anterior homeotic transformations of vertebral elements in
Hox5, Hox6, Hox9, Hox10 and Hox11
paralogous mutants. (A-C,F,G) Anterior views of
individual vertebrae from controls (upper row) and mutants (lower row) for
each set of paralogous mutants for Hox5 (A), Hox6 (B),
Hox9 (C), Hox10 (F), Hox11 (G). The position of
each vertebra in controls is indicated by C (cervical), T (thoracic), L
(lumbar), S (sacral) or Cd (caudal), followed by a number identifying its
position in each region. Vertebral elements anterior and posterior to those
shown in the figure appear identical to controls. (D,E) Dorsal
views of control (D) and Hox9 quadruple mutant (E) axial skeletons.
In the control mouse, the sacrum is immediately caudal to six lumbar vertebrae
(indicated by yellow stars on L1 and L6). In the Hox9 mutant, the
lumbar region is extended by two vertebral elements. The yellow stars in E
mark control positions of the first and sixth lumbar vertebrae.
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