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Fig. 7. Rescue of drl LOF MB defects using different
Drosophila GAL4 lines. All the lines analyzed are in the
lio2/drlR343 genetic background. In the
x-axis label, both the GAL4 line used and the absence (-) or
presence (+) of the UAS-drl construct are specified. n, the
number of brains analyzed. On the y-axis, the percentage of wild-type
brains is shown. MB morphology was assessed using the anti-FASII antibody.
P-values were obtained after
2 test comparisons. Only
the GAL4-c155 was able to rescue; the other GAL4 lines (247,
OK107 and 442) were unable to rescue the drl MB
phenotypes. These results indicate that the drl MB defects are linked
to the lack of expression of the drl RTK in neuronal cells extrinsic
to the MBs.