|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 2. Expression domains of skeletogenic markers in the developing dentary
bone. (A-J) HH39 chick embryos; (K-O) 16.5 dpc mouse embryos. Expression
of Coll II (A) and Coll IX (B) is detected in
cells of both Meckel's cartilage and dentary bone. (C) Expression of
Sox9 can be seen in cells of Meckel's cartilage but not in the
dentary bone. (D) Expression of Runx2 is limited to the cells
of the dentary bone. (E) Osteopontin is expressed in cells of dentary
bone but is restricted to the more mature cells. (F)
Bmp2,(G) Bmp4, (H) Ihh and (I)
strong expression of PTHrP-R are detected in the dentary bone.
(J) H&E staining of the dentary bone and Meckel's cartilage from
the embryo in A-I. In mice, (K) Coll II, (L)
Runx2 and (M) Osx are expressed in the peripheral
cells, whereas (N) the more mature osteoblast marker Opn is
expressed in cells surrounded by mineralized matrix (H&E stain; O).
dnt, dentary bone; MC, Meckel's cartilage. Scale bars: 200 µm.
|
