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Fig. 7. Summary. Regionalisation of the diencephalon. At mid-somitogenesis
stages, Otx1l/2 mark the presumptive ZLI (p-ZLI, light blue) and the thalamic
anlage (Th, yellow), whereas irx1b is expressed only in the thalamic
anlage. Shh marks the floor plate and basal plate (red) and starts to be
induced in the Otx1l/2-positive pZLI (green arrows). At pharyngula stages,
shh is expressed in the mature ZLI (red) and the territory of the
Shh-positive ZLI is restricted by the thalamic expression of irx1b
(red T-brackets).