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Figure 9


Fig. 9. Isolation of mesDA progenitors from ES cell-derived neural populations. (A) Surface expression of Corin in undifferentiated ES cells and SDIA-induced populations. (B) RT-PCR analysis of unsorted SDIA-induced cells (all) and sorted Corin+ and Corin- populations. Expression of undifferentiated ES cell-specific Nanog is not detected in the Corin+ population. (C) mesDA progenitors are enriched in the Corin+ population. Neurons generated from Corin+ cells show correct mesDA neuron identity. G3PDH, glyceraldehyde-3-phosphate dehydrogenase.





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