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Fig. 2. Wnt signaling in morphogenesis and cell polarity.
(A,B) A requirement for Ror2 in non-canonical Wnt signaling.
Elongation and constriction of Keller explants (dorsal tissue from
Xenopus gastrulae) used as a model of non-canonical Wnt5a signaling
(see text). (A) Uninjected explant. (B) Ror2 morpholino-injected explant shows
lack of constriction (arrows) during convergent extension movements. Image
courtesy of Alexandra Schambony. (C) Asymmetric WRM-1-GFP localization
during telophase in the V5.p cell of the C. elegans larva. Note
cortical localization of WRM-1 in the newly forming cell on the left (arrow)
and more-pronounced nuclear localization in its sibling cell on the right.
Image courtesy of Kota Mizumoto. (D) Asymmetric ß-catenin
localization in a 16-cell Platynereis dumerilii embryo. Animal pole
view; 
-tubulin (green), and histone (blue). Sister cells are connected
by white bars. Notice that ß-catenin (red) is present at high levels in
the nuclei of vegetal-pole sister cells (arrowheads, magenta color), but at
low levels in the nuclei of animal-pole sisters. Image courtesy of Stephan
Schneider. See text for references. Scale bars: 
150 µm in A for A,B; 2
µm in C.
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