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Figure 1


Fig. 1. Mouse Dprp gene, construction of a Dprp-null mutant targeting vector, genotype analysis, and Dprp mRNA and protein expression. (A) Exons 2-6 of the mouse Dprp gene were replaced with an in-frame EGFP gene followed by an MC1neo cassette. (B) PCR analysis of wild-type (+/+), heterozygous (+/-) and null (-/-) alleles. (C) RT-PCR analysis of Dprp transcripts in gestation day 7.5 decidua from wild-type (+/+) and Dprp-null (-/-) mice. (D) Western blot analysis of DPRP protein in gestation day 7.5 decidua from wild-type (+/+) and Dprp-null (-/-) mice.





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