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Figure 4


Fig. 4. Abnormal testicular development of the PU.1-negative mouse mutant. (Aa-g,Ba-g) Testis sections of PU.1+/+ (a,c,e) and PU.1G/G (b,d,f) littermates at E15.5 (A) and E17.5 (B). (Ag,Bg) The average number of gonocytes per transverse tubule section, for both developmental times. (C) RT-PCR assay for vasa and stella expression performed on RNA prepared from E18.5 PU.1G/G, PU.1G/+ and PU.1+/+ fetal testis. Scale bars: 50 µm.





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