DEV007930 Supplementary Material

Files in this Data Supplement:

• Supplemental Table S1 -

  Adobe PDF

• Supplemental Figure S1 (Adobe PDF) -

  Fig. S1. Tumour miRNA transcript levels. 'Heat map' clustering of tumour and wild-type miRNA profiles. Clustered profiles of miRNAs from tumours and wild-type (wt) placenta and ovary from the strain B6D2F₁.

• Movie 1 -

  Movie 1. Oocyte maturation occurs at the same speed in oocytes from wild-type and Plcz1 transgenic females. GV oocytes from wild-type (left) and hemizygous females were allowed to mature during culture in vitro. Images were captured every 10 minutes and the movie plays at 30 frames/second.

• Movie 2 -

  Movie 2. Ectopic PLCZ1 expression can induce ataxia. The movie shows hind-limb ataxia in the F₁ transgenic female, CV3-13, from the line CV3.