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Fig. 3. Timing and early in vivo consequences of rPLCZ1 expression.
(A) Epifluorescence microscopy of mouse ovarian follicle section
showing Venus expression (left) within a maturing primary oocyte (arrowhead),
stained for DNA (right). (B) Asynchronous parthenogenotes recovered
from hemizygotes 16 hours post-hCG. (C) Hematoxylin and Eosin staining
of an 11-week-old hemizygous ovary which appeared macroscopically normal, at
low and higher (inset) magnification, showing a nascent follicular
choriocarcinoma or yolk sac tumour. Scale bars: 50 µm in A,C; 20 µm in
B.
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