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Figure 6


Fig. 6. Histopathology of rPLCZ1-induced ovarian tumours. (A) Mature cystic teratoma (epidermoid cyst) with keratinisation. (B) Intestinal epithelium with goblet cells. (C) Neurectodermal rosettes with tubules and glia-like stroma. (D) Mixed germ cell tumour showing yolk sac tumour (right), choriocarcinoma (top) and dysgerminoma (left). (E) Dysgerminoma (right) with yolk sac tumour. (F) Nests of dysgerminoma cells with follicle. (G) Mucinous cystadenoma with borderline malignancy of columnar epithelium. (H) Mixed germ cell tumour showing yolk sac tumour (right) and choriocarcinoma (top). Sections stained with Hematoxylin and Eosin are from three CV3 (A-E) and two CS16 (F-H) F2 female mice. Scale bars: 100 µm.





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