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Fig. 6. The axial mesendoderm is subdivided into different territories with
complementary snail1 and E-cadherin (Cdh1) expression.
(A-H) Expression of snail1 genes and that of E-cadherin
protein. (A,B) At 70% epiboly, snail1a-expressing cells surround the
anterior limit of the hgg1- expressing domain and snail1b
transcripts are absent from the hgg1-expressing prechordal plate
region. (C,D) These expression domains are better observed in sections. (E)
The domain of strong snail1a expression surrounding the
hgg1-expressing cells is already present at 60% epiboly. (F) Diagram
depicting the domains of snail1a, 1b and hgg1 expression in
the anterior half of the embryo. (G,H) snail1b and E-cadherin (Cdh1)
expression in the posterior half of an embryo at 90% epiboly. Note the
complementary domains of snail1b and cadherin expression (compare E
with F). (I) Diagram showing the relationship between the expression of
snail1 genes and those of hgg1 and ntl. Also note
the inverse correlation between snail1 and Cdh1 expression.
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