spacer gif spacer gif spacer gif spacer gif ARCHIVE ANNOUNCEMENT! spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 3


Fig. 3. Inhibition of heparanase function by Ab733 is specifically rescued by FGF10. SMGs were cultured for 48 hours with 1 µl of function-blocking Ab733 (~IC50 number of end buds) and increasing doses (see Materials and methods for concentrations) of exogenous FGF1 (10 ng/ml), FGF2 (10 ng/ml), FGF7 (100 ng/ml), FGF10 (100 ng/ml) and HB-EGF (20 ng/ml) were added. The number of buds was expressed as a ratio of the number of buds at 48 hours/number of buds at 1 hour (T48/T1). At least five SMGs per condition were used and the experiment was repeated at least three times. ANOVA compared with the Ab733 alone, **P<0.01.





Right arrow Return to article