spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 8


Fig. 8. Model summarizing regulation of ooplasmic pHi by granulosa cell transport mechanisms. The small growing oocyte is incapable of regulating its own pHi, but the gap junctions, which couple the oocyte and granulosa, allow exchangers on the granulosa cell surface to regulate the ooplasm. Granulosa cell exchangers that participate are indicated: Na+/H+ exchanger isoform 1 (light gray circles), isoform 3 (dark gray), and V-ATPase (open circle). The molecular identity of the HCO3-/Cl- exchangers that regulate against alkalosis is unknown (black circles). The broad arrows indicate diffusion of proton equivalents between oocyte and granulosa (see text).





Right arrow Return to article