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Figure 8


Fig. 8. Double Ttrap and Smad3b knockdown rescues CE defect in Ttrap knockdown. myod marks paraxial/adaxial mesoderm (8 ss). (A) Broadened somites and a wide distance between myod cells in Ttrap single knockdown embryo. (B) A combination of 16 ng TtrapMO and 1 ng Smad3bMO shows closer convergence of myod cells at midline. However, somitic expression is still broad relative to the fully rescued embryo co-injected with 2 ng Smad3bMO (C), which now displays the normal myod domain. Dorsal views, anterior at top.





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