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Fig. 1. The neuropeptide signalling pathway at eclosion. In response to
decreasing levels of ecdysone, ecdysis-triggering hormone (ETH) is released,
triggering the release of eclosion hormone (EH). These hormones act together
in a positive-feedback loop, increasing the release of one another and
regulating pre-ecdysis behaviour. EH causes the release of crustacean
cardioactive peptide (CCAP), which shuts off pre-ecdysis and turns on the
ecdysis motor program. At eclosion, CCAP causes release of bursicon, which
binds to its receptor RK, and induces post-eclosion events by elevating levels
of cAMP and causing tanning. This figure is modified from Clark et al.
(Clark et al., 2004) and McNabb
et al. (McNabb et al.,
1997).
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