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Figure 6


Fig. 6. (A-A'') High levels of Ser expression (green) correspond with the loss of slp-lacZ (red) in third-instar eye discs. eyg-Gal4/UAS-GFP expression (blue) demarcates the eye field (dotted line indicates the anterior extreme of the eye); Ser expression anterior to this relates to patterning of head capsule tissues. Arrow in A' indicates the downregulation of slp expression in the ventral spur corresponding with high Ser expression. (B-B'') Ser (green) is expressed in cells not expressing mirr-lacZ (red), except in the most anterior regions (arrow in B''). (C-D'') The roles of N, Slp and Iro in regulating Ser upregulation in third-instar discs. (C) Ectopic expression of slp (red, arrow) in the region of the gap shows a downregulation of Ser expression (green). Note that slp does not repress Ser completely. (D) Ectopic expression of mirr in the region of the gap (red, arrow) shows a downregulation of Ser expression (green). Note that the non-autonomous induction of Ser (arrowhead) is likely to be caused by the new Fng+-Fng- interface induced in the ventral cells.





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