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Fig. 5. Diminished androgen dependency in Fgfr2cn prostates
with respect to tissue homeostasis. (A) Fgfr2cn
and control mice were orchiectomized to eliminate testisderived androgens. At
the indicated day after the operation, the prostate tissues were harvested and
apoptotic cells were detected with TUNEL assay. (B) HE staining of the
same tissues showing that castration failed to induce tissue atrophy in
Fgfr2cn prostates. F/F, homozygous
Fgfr2flox mice; CN, Fgfr2cn mice.