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Fig. 9. Summary of the convergent extension defect in Lp.
Mesodermal cells emerge from the node into the notochordal plate, where
midline intercalation leads to narrowing to form the notochord. In the
overlying neural plate, cells converge on the midline, where they extend in
the rostrocaudal axis. Red arrows: events that are disrupted in Lp/Lp
embryos: principally midline intercalation in cells emerging from the node and
convergent extension in the neural plate. Black arrows: events that appear to
occur normally in Lp/Lp embryos.
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