QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

	Help viewing high resolution images
	Return to article

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 3. Cort can mediate the destruction of mitotic regulators and its activity depends on Cks30A. (A-C') UAS-HA-Cort expressed under ptcGal4 and detected with anti-HA antibodies. Cyclin A (A'), cyclin B (B') and cyclin B3 (C') are reduced in the stripe, corresponding to Cort expression. (D,D') UAS-Fzy expressed under ptcGal4 (detected with anti-ß-gal antibodies; D) results in a corresponding reduction in cyclin A levels (D'). (E-H) Magnified area of an adult wing from Drosophila expressing HA-Cort (E,G,H) or UAS-Fzy (F) in the posteriorhalf of the wing (P) using enGal4. The anterior-half of the wing (A) serves as a control. Expression of UAS-HA-Cort (E) or UAS-Fzy (F) in the posterior wing results in a wider spacing of wing hairs. (G) Wing-hair-spacing phenotype is suppressed when HA-Cort is expressed in a Cks30A^KO/Cks30A^KO background. (H) Co-expression of UAS-Flag-Cks30A with HA-Cort in a Cks30A^KO/Cks30A^KO background restores the wing-hair-spacing phenotype. (I) Expression of Flag-Cks30A alone does not affect bristle spacing. Scale bar: 20 µm.

Return to article