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Fig. 1. SoxN loss of function suppresses wg mutant phenotypes. (A) Hypomorphic wg^NE2 mutation reduces the zones of naked cuticle, which separate denticle belts, on the ventral side and disrupts dorsal patterning, resulting in strong curvature of the embryonic cuticle. (B) SoxN^NC14 mutation rescues wg^NE2 ventral patterning to almost wild type (compare with Fig. 2A), without rescuing dorsal patterning. (C,D) The RNA-null wg^CX4 allele produces a `lawn of denticles' phenotype (C), which is partially suppressed by the SoxN^NC14 mutation (D). (E) wg^CX4 mutant embryos lose epidermal expression of the Wg target gene en before stage 10 (compare with wild-type pattern in Fig. 2G). (F) wg^CX4, SoxN^NC14 double-mutant homozygotes retain some epidermal en expression (arrows) even at late stages. SoxN^NC14 is linked to wg on the second chromosome; single and double homozygotes are recognized by the absence of GFP from a marked balancer chromosome. Embryos are oriented with anterior to the left and dorsal side up.

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