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Figure 9


Fig. 9. Notch signaling acts in a short time-window early in pronephric development. shippo1-positive multiciliated cells were counted at 34 hpf (in situ hybridization) in individual tubules. (A) Quantification of MCCs per pronephric tubule in experiments adding DAPT at progressively later times. (B) Quantification of MCCs per pronephric tubule in embryos induced to express Notch1a ICD by heat shock at 8 hpf and 9 hpf. See text for details.





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