spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 2


Fig. 2. Delayed radial migration of immature projection neurons in Zbtb20 transgenic mice. (A,G) Nissl-stained wild-type and Zbtb20 transgenic E18 coronal sections of medial-dorsal telencephalon. Compared with wild type (A), Zbtb20 transgenic embryos harbor streams of radial migrating cells in the intermediate zone (arrow in G). (B-F,H-L) Cell birth date and cortical migration analyses by indirect immunofluorescent detection of BrdU-labeled cells (arrows in B,C,H,I) and by fluorescent visualization of EGFP-labeled neurons in CP (arrows in D-F,J-L) at late P0 (D,E,J,K) and P14 (F,L) following in vivo transfection with a pCIG2-EGFP expression vector at E15, in coronal sections counterstained with DAPI. (M) Distribution of EGFP-labeled cells in P0 brains transfected with pCIG2-EGFP at E15.The data are presented as means±s.e.m. *, P=0.021, **, P=0.029, ***, P≤0.001. Deep, deep half of CP; Superficial, superficial half of CP.





Right arrow Return to article