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Figure 5


Fig. 5. Altered pattern of molecular marker expression in Zbtb20S transgenic cortex. (A,G) Low-magnification views of indirect immunofluorescent detection of Oct-6-labeled cells in coronal sections of P14 wild-type (A) and Zbtb20 transgenic (G) posterior cerebral cortex. (B,H) Higher-magnification views of A and G with focus on CA1, Sub and Rsc. (C,I) Immunohistochemical detection of ER81-labeled cells in coronal sections of P14 wild-type (C) and Zbtb20 transgenic (I) CA1, Sub and posterior Rsc. (D,E,J,K) Indirect immunofluorescent detection of Brn-1- and Brn-2-labeled cells in coronal sections of P0 wild-type (arrows in D and E) and Zbtb20 transgenic (J,K) posterior cerebral cortex. (F,L) High-magnification views of indirect immunofluorescent detection of reelin (arrows) in retrosplenial cortex of coronal hemisections of P0 wild-type (F) and Zbtb20 transgenic (L) brains. Insets (F,L), low-magnification views of indirect immunofluorescent detection of reelin in posterior cerebral cortex. (M-P) Indirect immunofluorescent detection of Brn-1 and Brn-2 expression in sub-pial nodules (arrows in N and P) of lateral areas of Zbtb20 transgenic visual cortex, counterstained with DAPI (M,O).





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