spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. cnox-2 acts as an upstream regulator of the nematocyte and neuronal differentiation pathways. (A) Colocalization of the cnox-2 (green) and hyZic (red) transcripts in nematoblast clusters (a-c) and dividing i-cells (e-g). After 9x cnox-2 dsRNA exposures, expression of cnox-2 and hyZic is either abolished (i-k, hydra1) or residual (m-o, hydra2). In cnox-2(-) hydra1, Kazal1 expression in gland cells (purple, l,p) is similar to control (d,h). Scale bars: 30 µm in a-d,i-o; 5 µm in e-h,p. (B) Expression of genes expressed in the nematocyte (left) and/or neuronal (right) cell lineages of hydra exposed 5x to control (lanes 1,3,5,7) or cnox-2 (lanes 2,4,6,8) dsRNAs. Number of cycles: 18 except hyZic (24), msh (16), hyCOUP-TF (16). (C) Scheme depicting the putative regulators of interstitial stem cells, neuronal progenitors, interstitial cells, neurons and nematoblasts. ic, interstitial cell; ISC, interstitial stem cell; nb, nematoblast; ne, neuron; NPG, neuronal progenitor.





Right arrow Return to article