spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. BMP4 rescues outgrowth of PTHrP-/- mammary buds in organ culture. (A-D) Representative examples of bud outgrowths after 7 days in organ culture. (A) Wild-type mammary bud. (B) PTHrP-/- bud. (C) PTHrP-/- bud treated with 10-7 M PTHrP. (D) PTHrP-/- bud treated with 10 ng/ml BMP4. (E) Quantification of the frequency of bud outgrowth under different conditions as noted on the x-axis. Each experiment was performed on 15 buds over three separate experiments, except for the wild-type buds, which represent a total of 40 buds over eight separate experiments. *, P<0.05 for WT versus WT+noggin; #, P<0.05 for WT versus KO; triangle, P<0.05 for KO versus KO+PTHrP and KO versus KO+BMP4.





Right arrow Return to article