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Figure 7


Fig. 7. Dual immunofluorescence analysis of PTCH1-positive and SMO-positive human DCIS and IBC. (A-F) PTCH1-Ki67 in DCIS and IBC. Representative staining patterns are shown that indicate extensive colocalization of PTCH1 with Ki67 in those samples expressing detectable PTCH1. (G-J) SMO-Ki67 in DCIS and IBC. Representative staining patterns are shown that indicate rare colocalization of SMO with Ki67 in those samples expressing detectable SMO. Arrows and arrowheads in G indicate SMO+ cells and Ki67+ cells, respectively. (K) Quantitative analysis of SMO-Ki67 colocalization in DCIS and IBC.





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