spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 7


Fig. 7. Purinergic receptor antagonism of BDNF-dependent spiral ganglion neurite development. Cultures of P4 spiral ganglion explants were treated for three days with medium (control) or with addition of BDNF at 1 ng/ml or 10 ng/ml. The effect of P2X receptor activation on BDNF-dependent neurite development was assessed with ATP{gamma}S (100 µM) and {alpha},ßMeATP (100 µM). (A-F) Immunofluorescence images of spiral ganglion explants labeled for neurofilament. BDNF at 10 ng/ml. Scale bars: 500 µm. (G,H) Experiments comparing BDNF-induced neurite growth with and without ATP{gamma}S (n=12-20 explants per group). (I,J) Experiments comparing BDNF-induced neurite growth with and without {alpha},ßMeATP (n=12 explants per group). *P<0.05; **P<0.01.





Right arrow Return to article