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Fig. 10. Shroom1 expression is sufficient to elicit apical accumulation of
-tubulin in naïve epithelial cells. (A) Surface view
of blastomeres stained for -tubulin. Shroom1-expressing cells (right)
accumulate high levels of -tubulin at cell-cell junctions. (B)
Section view of blastomeres stained for -tubulin. (b')
Shroom1-expressing cells [indicated by anti-Myc staining (red)] accumulate
excess -tubulin at cell-cell boundaries. (C) Model for
Shroom3-mediated cell shape changes in neural epithelial cells. Model is based
on data from the current work and also on the work of Hildebrand
(Hildebrand, 2005) and Haigo
et al. (Haigo et al.,
2003).
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