|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 2. A comparison of wild-type and Foxe3 mutant mouse eyes.
(A) Hematoxylin-Eosin (HE)-stained coronal section of a P14 wild-type
mouse eye showing a lens stained in pink. (B) An HE-stained coronal
section of a P1 eye from a dyl mouse showing an abnormal small lens,
cornea and retina (blue). (C,D) Coronal sections of eyes from
P14 Foxe3-/- mice showing abnormal features of the lens,
cornea and retina. Note the rudimentary lens (arrowed) in D. (E)
Cerebral magnetic resonance imaging (MRI) of a 3-year-old human subject with a
mutated FOXE3 gene, showing absence of the lens. (F) An
HE-stained section through the eye of a 3-month-old child with a mutated
FOXE3 gene, showing the absence of the lens (arrow). The asterisk
indicates the empty cavity, most likely corresponding to the vitreous. c,
cornea; l, lens; on, optic nerve; r, retina. A,C,D are reproduced with
permission from Medina-Martinez et al.
(Medina-Martinez et al.,
2005); B is from I. Brownell and M.J., unpublished; E,F are
reproduced with permission from Valleix et al.
(Valleix et al., 2006).
|
