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Fig. 7. Puf proteins nucleate the assembly of different repressor complexes in
Drosophila and budding yeast. Models of the mechanism by which
Pum and MPT5 repress CycB and HO mRNAs in
Drosophila and S. cerevisiae, respectively. The data of Figs
2 and
4 are consistent with the idea
that a germline-limited co-factor (magenta) binds directly to the
CycB NRE; however, other roles for the co-factor are possible.