spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. The Ripply2-knockout mouse exhibits segmentation defects. (A-D) Ripply2+/- and Ripply2-/- embryos (n=3 at E10.5) were compared by external morphology (A,B) and by the Hematoxylin and Eosin staining of parasagittal sections of tail regions (C,D). Ripply2-/- embryos display irregularly sized myotomes, and an unclear segmental border. (E-G) Skeletal preparations at E17.5 stained with Alizarin Red-Alcian Blue reveal that the Ripply2-/- fetus harbors fewer pedicles of neural arches and lacks components of the proximal ribs (F; n=4), which is similar to the aberrant phenotype of the Psen1-null fetus (G; n=2).





Right arrow Return to article