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Figure 6


Fig. 6. Endodermal Tbx1, Fgf8 and Bmp4 expressions appear normal in mutants. (A-C) In situ analysis for Tbx1 at E9.5 in Nkx2.5Cre/+; Shhflox/- (B) and Shh-/- (C) mutants appears normal within the pharyngeal endoderm when compared to control (A). (D-F,I,J) Similarly, mRNA levels for Fgf8 (D-F) and Bmp4 (I,J) also appear normal. (G-H') Fgf8lacZ expression is also grossly normal in Shh-/- pharyngeal endoderm (H) and OFT/right ventricle (H') when compared to controls (G,G').





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