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Fig. 8. Combinatorial actions of patterning and proneural/inhibitory HLH factors
in specifying neuronal and glial cell lineages. The activities of
individual transcription factors (patterning factors, left;
proneural/inhibitory HLH factors, top) and their combinations are summarized.
Arrows and blunt-ended lines indicate stimulation and inhibition,
respectively, of differentiation into specific cell types. The thickness of
each arrow arbitrarily reflects the strength of the activity. Olig,
oligodendrocyte.