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Fig. 6. p75NTR expression in sympathetic neurons is dependent on
CREB. Non-radioactive in situ hybridization with a riboprobe specific for
the p75NTR on representative sagittal sections from control
(A,C) and CrebDBHCre; Crem-/-
(B,D) showing the SCG (A,B) and basal cholinergic neurons (C,D)
at E17.5. Asterisk indicates the inner ear. Immunohistochemistry with an
antibody recognizing the p75NTR protein is used to analyze protein
expression in the SCG at E17.5 in controls (E) and in
CrebDBHCre; Crem-/- (F). Scale bar: 250
µm in A-D; 40 µm in E,F; 20 µm in insets.