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Fig. 1. Par-complex proteins are reduced at the ventricular surface during
cortical neurogenesis. (A-R) Coronal section through E12
(A-C,G-I,M-O) and E16 (D-F,J-L,P-R) mouse cerebral cortices immunolabeled for
Par3 (A-F, red), Par6 (G-L, red) or aPKC
(M-R, red), pan-cadherin
(green) and stained with DAPI (blue). Note the high immunoreactivity for Par3,
Par6 and aPKC
in the apical domain of the VZ at E12 and its reduction
at later developmental stages. Scale bar: 25 µm.