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Figure 2


Fig. 2. Localization of MALS immunoreactivity compared with other proteins in the VZ. (A-C) Immunostaining of E14 coronal sections of rat telencephalon reveals that MALS is localized supra-apical to F-actin. (D-F) CASK antibody did not reveal specific immunostaining in the VZ. (G-I) PALS1 is also localized supra-apical to F-actin, in a pattern similar to that of MALS. (J-L) CRB3 localization is similar to that of PALS1 and MALS. (M-O) Mint shows a diffuse yet apically biased localization in the VZ. (P-R) DLG, a protein localized basolaterally in many cell types, does not localize to the apical surface in NPCs. (S-U) F-actin colocalized with staining for pan-cadherin in the apical domains of VZ cells. Scale bar: 5 µm.





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